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血清DKK-1在结肠癌诊断中的临床意义 被引量：1

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摘要 探讨血清DKK-1在结肠癌诊断中的临床意义。选择2010年4月—2015年4月我院普通外科行结肠癌根治术的无远处转移的结肠癌患者98例为研究对象,并选择同期结肠腺瘤患者50例为腺瘤组,健康体检者50例为对照组,以酶联免疫吸附分析方法检测外周血清中DKK-1水平。结肠癌患者血清DKK-1水平显著低于腺瘤组及对照组(P<0.05);腺瘤组血清DKK-1水平低于对照组,但差异无统计学意义(P=0.123)。DKK-1可能成为结肠癌诊断的血清学标志物之一。
作者 李晓宁 宋瑞 王前 陈学谦 张惠卿
机构地区 河北省保定市第一中心医院普通外科
出处 《中国现代普通外科进展》 CAS 2016年第6期503-504,共2页 Chinese Journal of Current Advances in General Surgery
关键词 结肠肿瘤 DICKKOPF-1
分类号 R735.34 [医药卫生—肿瘤]
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参考文献12

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中国现代普通外科进展
2016年 第6期

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