硅基酮亚胺类化合物的合成

Synthesis of Imidoylsilanes

下载PDF

导出

摘要介绍了一种高效合成硅基酮亚胺的方法,通过硅锂试剂对亚胺酸酯加成,然后用1 mol/L HCl淬灭反应,以中等产率得到了一系列硅基酮亚胺化合物。 An efficient method for the synthesis of imidoylsilanes has been described. In the described synthetic protocol,nucleophilic addition of silyllithium reagent to imino esters followed by quenching with 1 mol / L HCl leads to a range of imidoylsilanes in moderate yields.

作者汤凡林朝阳曾永明卢崇道

机构地区昌吉学院化学与应用化学系中国科学院新疆理化技术研究所

出处《化学试剂》 CAS 北大核心 2016年第8期791-794,共4页 Chemical Reagents

基金国家自然科学基金资助项目(21372255)

关键词硅锂试剂亚胺酸酯硅基酮亚胺合成 silyllithium reagent imino esters imidoylsilanes synthesis

分类号 O621.3 [理学—有机化学]

引文网络
相关文献

参考文献12

1FRANZ A K,WILSON S O. Organsilicon molecules with medicinal applications[ J]. J. Med. Chem. ,2013,56 ( 2 ) : 388-405.
2RICHARDSON P G,HIDESHIMA T,ANDERSON K C. Bortezomib ( PS-341 ) : a novel, first-in-class proteasome inhibitor for the treatment of multiple myeloma and other cancers [ J ]. J. Med. Chem. , 2003,10 ( 5 ) : 361-369.
3FRANZ A K, DREYFUSS P D, SCHREIBER S L. Synthe- sis and cellular profiling of diverse organosilicon small molecules[J]. J. Am. Chem. Soc. ,2007,129(5) : 1 020- 1 021.
4CZYZEWSKI M,SELLARS J B,GULIASHVILI T,et al. The first intramolecular silene Diels-Alder reactions [ J ]. Chem. Commun. ,2014,50(22) :2 919-2 921.
5MIN G K, HERNANDEZ D, SKRYDSTRUP T. Efficient routes to carbon-silicon bond formation for the synthesis of silicon-containing peptides and azasilaheterocycles [ J]. Acc. Chem. Res. ,2013,46(2) :457-470.
6AKAMATSU C,YAMAUCHI A, KOBAYASHI T, et al. An improved synthesis of fluorinated imidoylsilanes [ J ]. Synthesis ,2006,37 ( 37 ) : 1 836-1 840.
7SECONI K, PIRAZZINI G, RICCI A, et al. Methanolysis of the benzylideneaniline derivatives ArC( MMe3 ) = NAr' (M = Si or Sn) [ J]. Chem. Inform. , 1981,12 (42) :985- 1 107.
8. JOUSSEAUME B, VILCOT N, RICCI A. Imidoylstan- nanes,improved preparation and uses as acylanion equiv- alent[J].J. Chem. Soc. Perkin. l ,1994,16(16 :2 283-2 288.
9MURAKAMI M,ITO H,ITO Y. The Preparation of [ 1- (arylimino) alkyl] zinc by the a-addition of organozinc to isocyanide[ J]. J. Org. Chem. , 1998,53 ( 17 ) : 4 158- 4 159.
10KONDO Y, SASAKI M, KAWAHATA M, et al. Enanti- oselective synthesis of c-silylimines by a chiral lithium amide[J]. J. Org. Chem. ,2014,79(8):3 601-3 609.

1蔚勇军,石等,常元庆,敬文勇,熊义富.氘氚化锂分解残渣中微量氚的回收[J].中国工程物理研究院科技年报,2003(1):336-337.
2罗立强,Marija Popovic.非常规X射线能量探测技术[J].岩矿测试,2006,25(1):49-54. 被引量：3

化学试剂

2016年第8期

浏览历史

内容加载中请稍等...

硅基酮亚胺类化合物的合成

参考文献12

相关作者

相关机构

相关主题

浏览历史