摘要
α-螺旋模拟物是一类重要的小分子蛋白质相互作用抑制剂。芳香齐聚酰胺类小分子α-螺旋模拟物具有许多优点,其研究工作近年来取得了较快的发展。本文综述了近几年来芳香齐聚酰胺类α-螺旋模拟物的最新研究进展。
α-Helix mimetics are an important class of small molecule inhibitors of protein-protein interactions. Small molecular α-helix mimetics derived from aromatic oligoamides have many advantages and achieved rapid development in recent years. The latest progress of α-helix mimetics based on aromatic oligoamides was reviewed.
出处
《化学通报》
CAS
CSCD
北大核心
2016年第8期719-722,共4页
Chemistry
