期刊文献+

脂肪细胞因子chemerin与心血管疾病关系的研究进展 被引量:11

下载PDF
导出
摘要 Chemerin是一种新型脂肪细胞因子,在多种组织及细胞中均有较高表达。研究表明,chemerin与炎症反应、免疫应答、胰岛素抵抗及氧化应激等密切相关,在高血压、高脂血症、冠状动脉粥样硬化性心脏病、心力衰竭等多种心血管疾病的发生、发展过程中发挥重要作用。
出处 《国际心血管病杂志》 2016年第4期213-216,共4页 International Journal of Cardiovascular Disease
基金 国家自然科学基金(81270252)
  • 相关文献

参考文献35

  • 1Gantz I, Konda Y, Yang YK, et al. Molecular cloning of a novel receptor (cmklrl) with homology to the chemotactic factor receptors [J]. Cytogenet Cell Genet, 1996, 74(4): 286-290.
  • 2Nagpal S, Patel S, Jacobe H, et al. Tazarotene-indueed gene 2 (rig2), a novel retinoid-responsive gene in skin [J]. J Invest Dermatol, 1997, 109(1): 91-95.
  • 3Samson M, Edinger AL, Stordeur P, et al. Chemr23, a putative ehemoattractant receptor, is expressed in monocyte-derived dendritic cells and maerophages and is a coreceptor for siv and some primary hiv-1 strains [J]. Eur J Immunol, 1998, 28(5): 1689-1700.
  • 4Wittamer V, Franssen JD, Vulcano M, et al. Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids [J]. J Exp Med, 2003, 198(7): 977-985.
  • 5Goralski KB, McCarthy TC, Hanniman EA, et al. Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism [J]. J Biol Chem, 2007, 282 (38): 28175-28188.
  • 6Wittamer V, Bondue B, Guillabert A, et al. Neutrophil-mediated maturation of chemerin: a link between innate and adaptive immunity [J]. J Immunol, 2005, 175(1) : 487-493.
  • 7Zabel BA, Allen SJ, Kulig P, et al. Chemerin activation by serine proteases of the coagulation, fibrinolytic, and inflammatory cascades [J]. J Biol Chem, 2005, 280 (41) : 34661-34666.
  • 8Du XY, Zabel BA, Myles T, et al. Regulation of chemerin bioactivity by plasma earboxypeptidase n, carboxypeptidase b (activated thrombinactivable fibrinolysis inhibitor), and platelets [J]. J Biol Chem, 2009, 284(2): 751-758.
  • 9Bozaoglu K, Bolton K, McMillan J, et al. Chemerin is a novel adipokine associated with obesity and metabolic syndrome [J]. Endocrinology, 2007, 148(10): 4687-4694.
  • 10Zhang R, Liu S, Guo B, et al. Chemerin induces insulin resistance in rat cardiomyocytes in part through the ERK1/2 signaling pathway[J]. Pharmacology, 2014, 94 ( 5-6): 259-264.

二级参考文献113

  • 1DU X Y, ZABEL B A, MYLES T, et al. Regulation of chemerin bioactivity by plasma carboxypeptidase N, carboxypeptidase B (activated thrombin-activable fibrinolysis inhibitor), and platelets[J]. J Biol Chem, 2009,284:751--758.
  • 2WITTAMER V, BONDUE B, GUILLABERT A, et al. Neutrophil-mediated maturation of chemerin., a link between innate and adaptive immunity[J]. J Immunol, 2005,175 :487 - 493.
  • 3GUAI.ILLO O, GONZALEZ-JUANATEY J R, LAGO F. The emerging role of adipokines as mediators of cardiovascular function: physiologic and clinical perspeetives[J].Trends Cardiovasc Med, 2007, 17:275--283.
  • 4LEHRKE M, BECKER A, GREIF M, et al. Chemerin is associated with markers of inflammation and components of the metabolic syndrome but does not predict coronary atheroselerosis[J]. Eur J Endocrinol,2009,161: 339 - 344.
  • 5SPIROGLOU S G, KOSTOPOULOS C G, VARA- KIS J N, et al. Adipokines in periaortic and epicardial adipose tissue: differential expression and relation to atherosclerosis[J].J Atheroscler Thromb, 2010,17: 115--130.
  • 6GORALSKI K B, SINAL C J. Elucidation of chemer in and ehemokine-like receptor-1 function in adipo- cytes by adenoviral mediated shRNA knockdown of gene expression[J].Methods Enzymol, 2009,460 : 289 --312.
  • 7BOZAOGLU K, BOLTON K, MCMILLAN J, et al. Chemerin is a novel adipokine associated with obesity and metabolic syndrome [J].Endocrinology, 2007, 148..4687-4694.
  • 8ERNST M C, SINAI. C J. Chemerin: at the cross roads of inflammation and obesity[J]. Trends Endocrinol Metab,2010,21 ..660-667.
  • 9WANG Z, NAKAYAMA T. Inflammation, a link between obesity and cardiovascular disease[J]. Mediators Inflamm, 2010,53 : 5 - 18.
  • 10BOZAOGLU K, SEGAL D, SHIELDS K A, et al. Chemerin is associated with metabolic syndrome phenotypes in a Mexican-American population[J]. J Clin Endocrinol Metab, 2009,94 : 3085- 3088.

共引文献49

同被引文献115

引证文献11

二级引证文献41

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部