局部药物治疗急性智齿冠周炎的临床疗效对比

Comparison on the Clinical Curative Effects of Local Medication in the Treatment of Acute Pericoronitis

目的观察盐酸米诺环素软膏和碘甘油治疗急性局限型下颌智齿冠周炎的临床效果。方法将120例下颌局限型智齿冠周炎患者随机分为两组,每组各60例。全部患者常规采用3%过氧化氢液和生理盐水交替冲洗后擦干,A组局部用盐酸米诺环素软膏,B组用1%碘甘油治疗智齿冠周炎,5 d后复诊观察临床效果。结果盐酸米诺环素软膏组总有效率达96.6%,碘甘油组总有效率达73.3%,总有效率A组明显优于B组(P<0.01)。结论盐酸米诺环素软膏在智齿冠周炎的治疗中明显优于碘甘油,且使用方便、安全、可靠。

OBJECTIVE To observe the clinical effects of treatment of acute topical type mandibular third molar pericoronitis by mino-cycline hydrochloride compared with iodine glycerol. METHODS 120 cases of acute mandibular third molar pericoronitis were select-ed and randomly divided into two groups. All cases were treated initial therapy, which local parts were washed with 3% hydrogen per-oxide, and physiological saline consecutively, and dried clearly. In the group A, minocycline hydrochloride was treated. The B groupwas treated with 1% iodine glycerol. The clinical effects were observed after the fifth day. RESULTS The A group＇s total effectiverate was 96.6%. It was obviously higher than that of the group B 73.3%.There was a significant difference（P〈0.01）. CONCLUSIONS The minocycline hydrochloride was an effective, convenient and safe medicine for treating acute pericoronitis.