颅脑损伤患者应激不良状况研究

Study of poor energency response in patients with traumatic brain injury

目的:探究颅脑损伤患者应激不良状况及其与预后的关系。方法:对我院收治的200例颅脑损伤患者,按照入院时格拉斯哥评分(Glasgow coma score,GCS)评分,分为轻型20例、中型50例、重型71例与特重型59例等4组患者,对4组患者的基础皮质醇(cortisol,COR)水平进行测定,并观察应激不良发生率。结果:4组患者的应激不良发生率分别为0.00%、10.00%、30.99%与50.85%,差异具有统计学意义(<0.05);4组患者的应激良好患者与应激不良患者的出院时GCS评分对比,差异均具有统计学意义(<0.05)。结论:颅脑损伤患者存在较高的应激不良发生率,可能与颅脑损伤的严重程度有关,应激不良可对患者的预后造成较大的影响,应引起临床重视。

Objective： To investigate the relationship between the stress conditions and prognosis of patients with traumatic brain injury.Methods： A total of 200 patients with craniocerebral injury in our hospital were divided into 4 groups：light types,20 cases;medium type,50 cases;heavy type,71;and most severe type,59 cases.according to the Glasgow score on admission （Glasgow coma score,GCS） score,and the cortisol levels of 4 groups were determined,and the incidence of adverse stress were observed.Results： The incidence of adverse stress in 4 groups were 0.00%,10.00%,30.99% and 0.00% respectively,the difference was statistically significant （P〈0.05）.The difference of GCS score in 4 groups between good stress and bad stress were statistically significant （P〈0.O5）.Conclusion： Patients with traumatic brain injury have higher incidence of adverse stress,which may be associated with the severity of craniocerehral injury,poor stress can cause great influence to the prognosis of patients,which should be paid attention during clinical.