鄱阳湖血吸虫病疫区人群肝脾肿大的流行病学调查

The epidemiological investigation onhepatosplenomegaly in the population ofschistosomiasis japonicaendemic area of Poyang Lake region

目的了解鄱阳湖血吸虫病流行区居民肝脾肿大情况。方法以B超和粪检方法对鄱阳县表波村居民同时进行检查。结果居民肝肿大率和纤维化率分别为16.1%和76.6%,男性高于女性,并随着年龄的增大而肝肿大/肝纤维化率都呈现增高的变化趋势。脾肿大率较高,20-岁以上年龄组均高于79%,男性也高于女性。渔船民肝肿大和肝实质纤维化Ⅱ级改变率分别为22.2%和36.5%,均高于其他职业人群。结论血吸虫病疫区人群肝脾肿大和纤维化率均较高,B超检查可以反映血吸虫病疫区人群肝脾病理变化。

Objective To understand the rate of hepatosplenomegaly of local residents inschistosomiasis japonicaendemic area of Poyang Lake region. Methods B ultrasound and microscopic examination were used to examine the residents lived in Biao Bovillage of PoYang county. Results The rates of hepatomegaly andliver fibrosis in the residents were 16.1% and 76.6% respectively,which were increased with age,and in male is higher than in female. The ratesofsplenomegalyinage groupabove 20 were all more than 79%,and inmale was also higher than in female. The changes of hepatomegaly and liver fibrosis of Grade Ⅱin the fishermen and boatmen were 22.2% and 36.5%,and the change ratesare higher than other occupations. Conclusion Bothhepatomegaly andliver fibrosis ratesarehighin local residentsin schistosomiasis japonicaendemic area. Ultrasonographycan reflect the pathological changes of liver and spleen.