参芪扶正注射液改善肝癌TACE治疗患者生活质量的临床观察

Clinical Observation of the Shenqi Fuzheng Injection in Improving of the Quality of Life of Patients with Liver Cancer Treated by TACE

目的经导管肝动脉化疗栓塞(TACE)是治疗不能手术的原发性肝癌的主要方法,但其严重发热及消化道症状等不良作用,严重影响了患者的生活质量,改善患者肝癌栓塞化疗后生活质量是需要面对的课题。方法将收治的90例符合纳入标准的60例原发性肝癌患者随机分为治疗组和对照组,对照组常规应用TACE治疗,治疗组则在TACE治疗的基础上加用参芪扶正注射液。结果治疗组临床症状及卡氏评分与对照组比较差异有显著性意义(P<0.05),不良反应与对照组比较差异有显著性意义(P<0.05)。结论参芪扶正注射液能够改善肝癌TACE治疗后患者躯体症状及生活质量,降低不良反应的发生。

Objective The transcatheter arterial chemoembolization（ TACE） is the main method for the treatment of primary hepatic carcinoma with no surgery. However,its severe fever and digestive tract symptoms and other side effects which seriously affect the quality of life of patients,improving the quality of life of patients with liver cancer after embolization chemotherapy is a problem needed to face.Methods 60 patients met inclusion criteria from 90 patients were randomly divided into study group and control group. The control group was treated with TACE,and the study group was treated with TACE and Shenqi Fuzheng injection. Results The clinical symptoms and the KPS score of the study group were significantly different from the control group（ P〈0. 05）,and adverse reactions was significantly different from the control group（ P〈0. 05）. Conclusion The symptoms and quality of life of patients with liver cancer treated by TACE were improved by the treatment of Shenqi Fuzheng injection,and the incidence of adverse reactions was decreased.