超声对乳腺癌新辅助化疗的效果评估

Evaluation of the effect on neoadjuvant chemotherapy for breast cancer patients using ultrasonography

目的探讨超声评估乳腺癌新辅助化疗（NAC）的价值。方法选取65例经NAC后手术的乳腺癌患者,超声测量NAC后肿瘤的最大长径,并与术后病理测量结果行Spearman相关分析和Kappa检验,分析患者生存预后情况。结果术前超声测量NAC后肿瘤大小与术后病理测量结果相关性较好（r=0.637,P=0.000）,一致性检验K=0.253,准确率为69.2%。患者随访19~90个月,局部复发和远处转移者20例,死亡2例。结论术前超声测量NAC肿瘤大小评估乳腺癌患者NAC反应有一定价值。

Objective To assess the effect of the neoadjuvant chemotherapy（NAC） on breast cancer using ultrasonography. Methods Altogether 65 patients underwent NAC were enrolled in this study. The longest diameter of tumour was measured using ultrasonography after NAC treatment. The correlation analysis was performed using Spearman method and Kappa test. The survival and prognostic conditions were analyzed.Results The size of residual tumour after NAC measured using US was significantly correlated to that measured by pathologists（r=0.625,P=0.000）,the difference of consistency was not significant（K=0.253）, and the accuracy was 69.2%.The patients were followed for 19~90 months,local recurrence and distant metastasis occurred in 20 cases and 2 of them were died.Conclusion It is feasible to evaluate the effect of NAC on breast cancer by ultrasonography.