摘要
目的 了解不良反应发生的特点,为安全用药提供参考。方法 对2014~2015年本院收集上报的917例不良反应报告进行分类统计和分析。结果 917例报告中,41~80岁人群不良反应发生率较高,占61.1%;通过静脉途径给药引发的不良反应最高,占到85.4%;涉及的19余种药物中,抗菌药物所占比例最高,达22.9%,其次为中成药制剂,占15.6%,其中涉及的31种抗菌药物中又以头孢菌素类不良反应发生率最高,占19.0%,而归属于喹诺酮类的药物左氧氟沙星引发的不良反应例数最多,为34例;累及器官或系统中皮肤及附件的损害最多,占50.6%,消化系统损害次之,占24.8%。结论 应继续加强对不良反应的监测,提高合理用药水平,减少ADR的发生。
Objective To explore the characteristics of adverse reactions, and provide reference for safe medication. Methods Nine hundred-seventeen cases of adverse reaction reports during 2014 to 2015 were classified statistics and analysis. Results Among 917 cases, the adverse reaction between 41 to 80 years old population rate is higher, accounting for 61.1%; adverse reaction caused by intravenous administration of most, accounted for 85.4%; more than 19 kinds of drugs involved, antibacterial drugs accounts for the proportion to be highest which is up to 22.9%, followed by the prepara- tion of traditional Chinese medicine, accounting for 15.6%, of which 31 kinds of antibiotics drug involved in cephalosporins adverse reaction rate was the highest, accounted for 19%, the adverse reactions of levofloxaein which belongs to the adverse reactions of quinolones cases up to 34; involving the skin and its appendages damage in the most, accounting for 50.6%, digestive system damage were the second, accounted for 24.8%. Conclusion We should continue to strengthen the monitor- ing of adverse reactions, improve the level of rational drug use, reduce the incidence of ADR.
出处
《临床医学研究与实践》
2016年第14期143-144,161,共3页
Clinical Research and Practice
关键词
药物不良反应
不良反应监测
合理用药
adverse drug reaction
ADR monitoring
the rational use of drugs