黄酮类化合物降糖功能研究进展

Research Advances in Hypoglycemic Functions of Flavonoids

黄酮类化合物是存在于水果和蔬菜中的多酚类化合物,越来越多的研究表明摄入富含黄酮食物与疾病预防有密切关系。对黄酮类化合物降糖功能的最新研究进展进行了综述,包括黄烷-3-醇、花青素、黄酮醇、黄酮类和异黄酮类,表明黄酮类化合物有降脂降糖、改善胰岛素抵抗、抑制相关葡萄糖代谢酶活性和抗糖尿病氧化损伤等作用。

Flavonoids are polyphenolic compounds that are abundant in fruits and vegetables .Increasing evidences demonstrate that a positive relationship exists between the consumption of flavonoid-rich foods and the disease prevention.In this research , we reviewed the research ad-vances in hypoglycemic functions of flavonoids, including flavan-3-ols, anthocyanidins, flavonols, flavones and isoflavone.This indicated that flavonoids had the functions of lowering lipid degradation and blood glucose, improving insulin resistance, inhibiting the activity of related glu-cose metabolism enzyme, resisting to diabetic oxidative damage and so on.