首发精神分裂患者血清心肌酶活性检测的临床价值

The Clinical Value of the Detection of Serum Myocardial Enzyme Activity in the First Episode Schizophrenic Patients

目的探讨首发精神分裂患者血清心肌酶活性检测的临床价值。方法选取35例首发精神分裂症患者和35名健康体检者分别作为观察组和对照组,对两组人员进行采血检测血清心肌酶活性、包括肌酸激酶、肌酸激酶同功酶、谷草转氛酶、乳酸脱氢酶及a-羟丁酸酸脱氢酶含量,记录数据并对比分析。结果观察组治疗前的血清心肌酶活性明显高于对照组,差异具有统计学意义(P<0.05);观察组治疗后血清心肌酶活性较治疗前明显降低,与对照组比较差异无统计学意义(P>0.05)。结论首发精神分裂症患者血清心肌酶活性测定对判断患者病情及评定疗效有一定的临床价值,值得讨论研究。

Objective To investigate the clinical value of the detection of serum myocardial enzyme activity in ifrst episode schizophrenic patients. Methods A total of 35 cases of first-episode split patients were used as observation group, and 35 healthy people were used as control group.Blood samples were taken for measurement of serum myocardial enzyme activity of two groups of researchers, including creatine kinase, creatine kinase isoenzyme, aspartate turns atmosphere enzyme, lactic dehydrogenase （LDH） and alpha hydroxy butyric acid dehydrogenase levels, record the data and comparative analysis. Results Observation group before treatment the serum myocardial enzyme activity was significantly higher than that of the control group, the difference was statistically signiifcant （P〈0.05）;Serum myocardial enzyme activity were observed after the treatment group compared with those before treatment was significantly lower, compared with the control group, the difference was not statistically significant （P〉0.05）. Conclusion The determination of serum myocardial enzyme activity in patients with first episode schizophrenia has a certain clinical value in judging the patient＇s condition and evaluating curative effect.