5-氨基酮戊酸光动力疗法治疗男性尿道口尖锐湿疣临床疗效研究

Clinical Efficacy of ALA-PDT in the Treatment of Condyloma of Male Urethral Orifice

目的：观察分析5-氨基酮戊酸光动力疗法（ALA-PDT）治疗男性尿道口尖锐湿疣（CA）的临床疗效。方法选择2016年3～6月我院收治的40例男性尿道口尖锐湿疣患者，采用ALA-PDT进行治疗。治疗结束后，评价临床疗效，并观察治疗期间的不良反应。结果本组40例患者中，完全缓解23例（57.5%），部分缓解14例（35.00%），无效3例（7.5%），有效率为92.50%（37/40）。结论采用ALA-PDT治疗男性尿道口尖锐湿疣具有良好的临床疗效，安全性较高。

Objective To observe and analyze the clinical effect of 5-amino acid photodynamic therapy （ALA-PDT） in the treatment of condyloma （CA） in male urethral orifice. Methods From March 2016 to June 2016, 40 cases of male patients with condyloma in male urethra in our hospital were selected, using ALA-PDT for treatment. After the end of treatment, the clinical efifcacy was evaluated, and the adverse reactions were observed during the treatment period. Results In this group, complete remission was seen in 23 （57.5%）, partial remission in 14 patients （35%）, 3 cases （7.5%） were ineffective, and the effective rate was 92.50% （37/40）. Conclusion The use of ALA-PDT in the treatment of male urethral orifice has good clinical curative effect, high safety.