摘要
目的对硝苯地平缓释片与苯磺酸左旋氨氯地平治疗轻中度原发性高血压的疗效及安全性分析。方法 200例轻中度原发性高血压患者,随机分为甲组100例(硝苯地平缓释片),乙组100例(苯磺酸氨氯地平片)。结果治疗后,两组血压均明显降低;乙组用药不良反应率(10.0%)明显低于甲组(22.0%),差异具有统计学意义(P<0.05);两组有效率比较,差异无统计学意义(P>0.05)。结论苯磺酸左旋氨氯地平和硝苯地平缓释片均能够控制血压,但苯磺酸左旋氨氯地平的用药不良反应较低,更加适合轻中度原发性高血压病的治疗。
Objective To analyze the efficacy and safety of nifedipine sustained-release tablets and levamlodipine besylate in the treatment of mild to moderate essential hypertension (EH). Methods 200 cases of patients with mild to moderate EH, were randomly divided into group A with 100 cases (nifedipine sustained-release tablets), and group B with 100 cases (amlodipine besylate tablets). Results After treatment the blood pressure signiifcantly decreased in both groups. Adverse drug reactions in patients of group B (10.0%) was signiifcantly lower than Group A (22.0%), the difference was statistically signiifcant (P〈0.05);Two groups of efifcient comparative difference had no significant (P〉0.05). Conclusion Both levamlodipine besylate and nifedipine sustained-release tablets are able to well control blood pressure, but levamlodipine besylate has fewer adverse drug reactions, which is more suitable for treatment of mild to moderate essential hypertension.
出处
《中国继续医学教育》
2016年第21期160-161,共2页
China Continuing Medical Education
关键词
苯磺酸左旋氨氯地平
硝苯地平缓释片
原发性高血压
Levamlodipine besylate
Nifedipine sustained-release tablets
Essential hypertension