早期使用免乳糖配方奶喂养早产低体质量儿的临床分析

Early Use of Lactose Free Formula in Low Birth Weight Preterm

目的：探讨免乳糖配方奶在早产儿喂养中的作用。方法：选取2010年1月至2014年12月我院收治的胎龄28-34周、体质量1 000-1 800 g的早产低体质量儿128例,随机分为观察组和对照组,观察组早期使用免乳糖奶粉喂养,对照组常规使用早产儿奶粉喂养。结果：观察组达到全肠道喂养时间及恢复至出生体质量时间为（11.11±2.43）d及（9.93±1.92）d,均较对照组明显缩短（P〈0.01）;观察组喂养不耐受与坏死性小肠结肠炎发生率与对照组比较差异均无统计学意义（P均〉0.05）。结论：早产儿生后早期使用免乳糖配方奶喂养可降低喂养不耐受发生率,缩短达到全胃肠喂养的时间。

Objective： To explore the role of lactose free formula in low birth weight premature infants. Methods： One hundred and twenty eight low birth weight premature infants with gestational age at 28 to 34 weeks,with weight in 1,000 to 1,800 grams were selected in our hospital from January,2010 to December,2014. All premature infants were randomly divided into two groups,the observation group and the control group. Observation group was given lactose free formula in early stage. The control group was given premature infant formula. Results： The time of enteral feeding in premature infants and returning to birth weight in observation group were（ 11.11±2.43） days and（ 9. 93 ± 1. 92） days,there were statistically significant differences between two groups（ P〈0. 01）. The incidence of feeding intolerance and NEC of observation group were not different between two groups（ P〉0. 05）. Conclusion： Early lactose free formula feeding,which can reduce the incidence of feeding intolerance and shorten the time of enteral feeding.