王坤根教授诊治慢性便秘规律的数据挖掘研究

Study on Professor Wang Kungen's Therapeutic Principles in Treating Chronic Constipation Based on Data Mining

[目的]利用数据挖掘技术探讨王坤根教授对慢性便秘的证治规律。[方法]建立王坤根教授2008年5月至2015年8月慢性便秘的门诊医案数据库,对数据规范化处理后进行频数分析、关联规则分析等数据挖掘研究。[结果]符合纳入、排除标准医案共207则,主要证型依次是胃肠积热证、肝郁脾虚证、阴液不足证和中气不足证,主要方剂依次是六磨汤、逍遥散、脾约丸和补中益气汤,方证间六磨汤与胃肠积热证、逍遥散与肝郁脾虚证、脾约丸与阴液不足证、补中益气汤与中气不足证存在较强的关联性,药对间生白术与大力子、生白术与生白芍、火麻仁与广木香、苍术与茯苓、桃仁与丹皮、莱菔子与枳壳存在较强关联性。[结论]慢性便秘的证型较为单一,泻热存津法、疏肝和胃法、健脾润肠法、补气行气法是王坤根治疗慢性便秘的主要治法。

[Objective] To study Professor Wang Kungen＇s therapeutic principles in treating chronic constipation by data mining therapy. [Method]First,establish Wang Kungen＇s medical records database; then do data standardization and data mining. [Result]There are totally 207 cases that meet the demand.The major patterns of syndrome of CC in Professor Wang Kungen＇s medical records are as follows： gastrointestinal heat syndrome, stagnation of liver qi and spleen deficiency, Yin deficiency syndrome, Qi deficiency. The major prescriptions are as follows： Liumo Decoction, Xiao Yao San, Pi Yue Pill, Buzhong Yiqi decoction. There is close correlation between prescriptions and patterns as follows： gastrointestinal heat syndrome and Liumo Decoction; stagnation of liver qi and spleen deficiency and Xiao Yao San; Yin deficiency syndrome and Pi Yue Pill; Qi deficiency and Buzhong Yiqi decoction. There is close correlation between herbs as follows： rhizoma atractylodis macrocephalae and fructus arctii; rhizoma atractylodis macrocephalae and radix paeoniae alba; fructus cannabis and elecampane; rhizoma atractylodis and fuling; peach kernel and cortex moutan; semen raphani and fructus aurantii.[Conclusion] The evidence type of chronic constipation is relatively purging heat and keeping body fluid, soothing the liver and stomach, tonifying spleen and moistening intestines,tonifying Qi.