摘要
发展了一种四丁基碘化铵(TBAI)催化的β-酰胺基酮类化合物氧化脱氢合成Z-β-酰胺基烯酮的方法.该方法具有反应条件温和,选择性高,原料易得,底物范围广等特点.这是首次报道的TBAI与过氧叔丁醇(TBHP)的氧化组合完成的氧化脱氢反应.
A tetra-butyl ammonium iodide （TBAI）-catalyzed oxidative dehydrogenation offl-acylamino ketones for the synthesis of Z-β-acylamino enones has been developed. The present method has some distinct advantages such as mild conditions, high selectivity, readily available starting materials, and broad substrate scope. This method is also the first example of oxidative dehydrogenation with the use of TBAI/TBHP （tert-butyl hydroperoxide） oxidation system.
出处
《有机化学》
SCIE
CAS
CSCD
北大核心
2016年第7期1681-1685,共5页
Chinese Journal of Organic Chemistry
基金
山西省科技攻关(No.20130313015-2)资助项目~~
关键词
碘离子
催化脱氢
β-酰胺基烯酮
立体选择性
iodide
catalytic dehydrogenation
β-acylamino enones
stereoselectivity
