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老年脑梗死泌尿系感染患者白介素与组织因子的变化研究 被引量:5

Changes of serum and urine interleukins and tissue factors of elderly patients with cerebral infarction and urinary tract infection
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摘要 目的研究老年脑梗死合并泌尿系感染患者血清及尿液白介素(IL)及组织因子的变化,为该类老年患者泌尿系感染的预防和治疗提供参考依据。方法选取2014年5月-2015年9月医院60例老年脑梗死合并泌尿系感染患者为观察组,同期选取60例老年脑梗死患者为对照组,比较两组患者的血清及尿液白介素及组织因子水平,数据采用SAS 6.0软件进行统计分析。结果观察组血清及尿液IL-1β、IL-6、IL-8、IL-10及TF水平分别为(3.45±0.42)(16.36±1.89)(18.52±2.20)(28.98±3.04)pg/ml及(1.64±0.21)U/L,均高于对照组,且观察组不同感染程度及感染部位者血清及尿液检测结果差异均有统计学意义(P<0.05)。结论老年脑梗死合并泌尿系感染患者血清及尿液白介素及组织因子呈现高表达状态,不同感染程度及感染部位者的血清及尿液检测结果也存在明显差异,应给予充分的重视及干预。 OBJECTIVE To study the changes of serum and urine interleukins and tissue factors of elderly patients with cerebral infarction complicated with urinary tract infection,in order to provide evidence for the prevention and treatment of elderly patients with cerebral infarction complicated with urinary tract infection.METHODS A total of 60 elderly patients with cerebral infarction complicated with urinary tract infection in hospital from May 2014 to Sep.2015 were selected as observation group,another 60 elderly patients with cerebral infarction at the same time were selected as control group,then the serum and urine interleukins and tissue factors of the two groups were compared.The data were analyzed by SAS 6.0.RESULTS The serum and urine IL-1β,IL-6,IL-8,IL-10 and TF levels of observation group were(3.45±0.42)pg/ml,(16.36±1.89)pg/ml,(18.52±2.20)pg/ml,(28.98±3.04)pg/ml,and(1.64±0.21)U/L,respectively,which were all higher than those of control group,and the serum and urine detection results of observation group with different infection degree and infection sites had significent differences too(P〈0.05).CONCLUSIONThe serum and urine interleukins and tissue factors of elderly patients with cerebral infarction complicated with urinary tract infection show high expression state,and the serum and urine detection results of patients with different infection degree and infection sites have obvious differences too,so they should be paid enough attention and intervention too.
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2016年第15期3428-3430,共3页 Chinese Journal of Nosocomiology
基金 河南省科技厅基金资助项目(201348907G)
关键词 老年脑梗死 泌尿系感染 血清 Elderly patients with cerebral infarction Urinary tract infection Serum
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