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三阴性乳腺癌组织中表皮生长因子受体E-黏钙蛋白的表达及意义

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摘要 乳腺癌是女性常见的恶性肿瘤之一,其发病率及死亡人数逐年增多。三阴性乳腺癌(triple negative breast cancer),即缺乏雌激素受体(ER)、孕激素受体(PR)及无Her-2的表达,占所有乳腺癌的10%~20%[1],侵袭性强,预后差,对激素拮抗剂和Her-2分子靶向治疗均无效,目前没有针对性治疗方案[2],迫切需要寻找合适的指标指导临床治疗及评估预后。目前,临床有很多蛋白表达和乳腺癌有相关性,本研究通过对表皮生长因子受体(EGFR)、E-黏钙蛋白2种蛋白的表达和三阴性乳腺癌的相关性研究,为临床诊治及评估提供依据。
作者 陈凯
出处 《实用医技杂志》 2016年第8期863-864,共2页 Journal of Practical Medical Techniques
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