外阴血管肌纤维母细胞瘤临床分析

Clinical feature of vulval angiomyofibroblastoma

目的分析外阴血管肌纤维母细胞瘤的临床及病理特征、治疗及预后。方法收集7例外阴血管肌纤维母细胞瘤,总结其临床表现、病理特征、治疗及预后,并结合国内外相关文献分析其发病机制及临床特征。结果 7例患者临床症状主要为逐渐增大的无痛性外阴肿物,病理大体标本境界清楚,组织学上呈密集血管区与少细胞的水肿区交替分布。手术治疗为主,预后良好。结论外阴血管肌纤维母细胞瘤罕见,术前易误诊,超声可辅助诊断,治疗首选手术,术后需长期随访。

Objective To study the clinical and pathological feature of vulval angiomyofibroblastoma, and discuss the treatment and prognosis. Method Clinical and pathological manifestations of 7 patients with vulval angiomyofibro-blastoma were included in the analysis, of which the clinical manifestations, pathological features, treatment and progno-sis were summarized, and the pathogenesis and clinical characteristics of the disease were investigated on the basis of do-mestic and foreign literatures. Result Of the 7 patients, the characteristic of angiomyofibroblastoma was gradually en-larged vulva tumor without pain and specific pathological feature. Anginomyofibroblastoma was well circumscribed, and characterized by alternating hypercellular and hypocellular edematous zones. It could be cured completely by surgery with good prognosis. Conclusions Vulval angiomyofibroblastoma is a rare tumor with frequent misdiagnosis before sur-gery. Ultrasound is preferred in auxiliary diagnosis and the best treatment is surgery, while long-term follow-up is needed.