不同雾化吸入药物治疗老年慢性支气管炎的临床疗效分析

Analysis of clinical effects by different aerosol inhalation drugs in the treatment of senile chronic bronchitis

目的探究不同雾化吸入药物治疗老年慢性支气管炎的临床疗效。方法 40例典型慢性支气管炎患者,采用随机数字表法分成试验组和对照组,各20例。试验组采用盐酸氨溴索(沐舒坦)联合布地奈德吸入的治疗方案,对照组采用布地奈德单独吸入的治疗方案。观察两组患者症状缓解时间及总有效率等情况。结果试验组咳嗽缓解时间为(5.2±1.1)d、喘息缓解时间为(4.9±1.3)d,短于对照组的[(8.2±1.9)、(7.2±2.1)d](P<0.05);试验组总有效率为75.00%,高于对照组的50.00%(P<0.05)。结论沐舒坦联合布地奈德使用对治疗老年慢性支气管炎有更积极的影响,可减轻患者痛苦,有效改善肺功能,值得推广。

Objective To investigate clinical effects by different aerosol inhalation drugs in the treatment of senile chronic bronchitis.Methods A total of 40 patients with typical chronic bronchitis were divided by random number table into experimental group and control group, with 20 cases in each group. The experimental group received ambroxol hydrochloride （mucosolvan） combined with budesonide inhalation, and the control group received single budesonide inhalation. Symptom relief time and total effective rate were observed in both groups.Results The experimental group had obviously shorter cough relief time as （5.2±1.1） d and gasp relief time as （4.9±1.3） d than （8.2±1.9） and （7.2±2.1） d of the control group （P〈0.05）, and its total effective rate was higher as 75.00% than 50.00% of the control group （P〈0.05）.Conclusion Combination of mucosolvan and budesonide shows active effect in treating senile chronic bronchitis. This method can relieve pain and improve pulmonary function, and it is worth promoting.