高场术中核磁共振联合神经导航在胶质瘤显微手术中的应用

Application of high-field intraoperative magnetic resonance imaging combined with neuronavigation in gli-oma micrurgy

目的：探讨高场术中核磁共振（M RI ）联合神经导航在胶质瘤显微手术中的临床应用价值。方法回顾性分析2011年8月～2015年3月延安大学附属医院收治的胶质瘤患者80例，按照手术方式分为观察组与对照组。观察组42例患者在高场术中M RI联合神经导航下进行胶质瘤显微切除术，对照组38例患者行传统胶质瘤切除术。对两组患者围术期情况、治疗效果、术后并发症及生活质量评分进行比较。结果观察组患者的手术时间、下床活动时间、住院时间、术中出血量及术后引流量均少于对照组，差异有统计学意义（P ＜0．05）。治疗后两组生活质量恢复情况的差异无统计学意义（P＞0．05）。观察组患者术后并发症发生率为16．67％，低于对照组的44．74％，差异有统计学意义（ P ＜0.05）。结论高场术中M RI联合神经导航下进行显微切除术治疗胶质瘤定位及切除准确，疗效好，安全性高，值得临床推广应用。

Objective To explore the application value of high -field intraoperative magnetic res‐onance imaging combined with neuronavigation in glioma micrurgy .Methods Eighty patients with glio‐ma from August 2011 to March 2015 were retrospectively analyzed and divided into observation group and control group according to the methods of surgery .Fouty two patients in observation group under‐took high-field intraoperative magnetic resonance imaging combined with neuronavigation in glioma mi‐crurgy ,and 38 patients in control group undertook traditional glioma excision .The perioperative institu‐tion ,efficacy ,complication rate and life quality scores of two groups were compared .Results The sur‐gery time ,activity time out of bed ,hospital stays ,blood loss and post -operation drainage of observa‐tion group were less than control group with statistically significance （P〈 0 .05） .No statistically signifi‐cance was found in improvement of life quality between two groups （P〉0 .05） .The complication rate of observation group （16 .67% ） was obviously less than the control group （44 .74% ） with statistically sig‐nificance （P 〈 0 .05） .Conclusions High -field intraoperative magnetic resonance imaging combined with neuronavigation is good at precise location and excision ,which has good efficacy and safety in clini‐cal application .