2011—2015年天津市职业病防治院抗抑郁药使用情况分析

Analysis on usage of antidepressants in Tianjin Occupational Diseases Precaution and Therapeutic Hospital during 2011—2015

目的探讨天津市职业病防治院抗抑郁药的使用情况及变化趋势,为促进临床合理用药提供依据。方法对天津市职业病防治院2011—2015年抗抑郁症用药的用药金额、用药频度(DDDs)、日均费用(DDC)和用药科室分布等进行统计分析。结果抗抑郁药的用药金额和DDDs总体上均呈现逐年增长的趋势;临床上抗抑郁药以合资和进口药品为主,国产药品占比较小,但逐年有小幅增长;除2013年外,舍曲林一直是DDDs值最高的品种。大部分抗抑郁药物的DDC值相对稳定,有部分抗抑郁药的DDC值在2013年发生下降。2014、2015年用药科室数量均减少到8个,且抗抑郁药DDDs排名第1位的一直是心理科门诊。结论 2011—2015年天津市职业病防治院抗抑郁药的应用基本合理,新型抗抑郁药是临床首选,用药空间广泛。

Objective To discuss the use and trends of antidepressants in Tianjin Occupational Diseases Precaution and Therapeutic Hospital, in order to provide reference for rational drug use in clinic. Methods Consumption sum, frequency of drug use（DDDs）, average daily cost（DDC）, and distribution of medicine department were analyzed statistically. Results Consumption sum and DDDs both showed an increasing tendency year by year. Main antidepressants in clinic were drugs of import and joint investment, while those made in China accounted for the relatively small, but had a slight increased year by year. Except 2013, DDDs of sertraline ranked the first during 2011 — 2015. DDC of most antidepressants was stable, while DDC of some drugs decreased in 2013. The number of medicine department both decreased to eight in 2014 and 2015. DDDs of Department of Psychologist always ranked the first. Conclusion The utilization of antidepressants in Tianjin Occupational Diseases Precaution and Therapeutic Hospital during 2011 — 2015 is basically rational. New antidepressants are the first choice in clinic, and have broad growth space.