摘要
支气管哮喘(哮喘)是一种异质性疾病,具有可变的呼吸道症状和可变的气流受限,还有不同的表型,故哮喘管理需要个体化策略。哮喘的个体化治疗策略基于疾病的不同严重度选择不同的治疗方案,同时评估患者的依从性、吸药技术、是否存在合并症等个体因素,并分别加以个体化处理,提供个体化哮喘行动计划和自我管理方案。对于重度哮喘,根据其不同的表型,给予精准的个体化方案。以患者为中心,根据疾病不同表型的个体化治疗策略可以使哮喘达到最大程度的控制。
Asthma is a heterogeneous disease with variant respiratory symptoms and flow limitation and different phenotypes, so individualized strategies are necessary for asthma management. The individualized treatment strategies for asthma are based on the severity of disease and evaluation of individual factors, including compliance of the patient, drug inhalation skills and complications, to provide individualized treatment, individualized asthma behavior plans and self-management programs. The precise individualized strategies are required for severe asthma according to different phenotypes. The patient-centered and phenotype-dependent individualized treatment strategies can achieve the most control of the asthma.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2016年第8期640-642,共3页
Chinese Journal of Practical Internal Medicine
基金
上海市科委自然科学基金项目(14ZR1406200)
关键词
支气管哮喘
个体化治疗
慢病管理
表型
bronchial asthma
individualized treatment
chronic disease management
phenotype