尿激酶联合芪苈强心胶囊治疗老年心肌梗死的临床观察

Urokinase combining with Qili Qiangxin capsules in the treatment of elderly patients with myocardial infarction

目的:探究尿激酶联合芪苈强心胶囊治疗老年心肌梗死患者的临床效果。方法:选取在我院住院治疗的80例老年心肌梗死患者,随机分为治疗组与对照组,每组40例。对照组患者给予尿激酶静脉滴注等常规疗法,在对照组基础上,治疗组加用芪苈强心胶囊。观察两组患者治疗前与治疗4周后血浆脑钠肽(BNP)含量变化,所有患者均随访5个月,观察2组患者的不良反应发生情况。结果:治疗4周后,两组患者BNP含量都明显降低(P<0.05);治疗4周后,治疗组患者BNP含量与对照组相比较,治疗组明显偏低,存在显著性差异,(P<0.05);随访5个月观察发现,与治疗组相比,对照组不良反应发生率较高(P<0.05)。结论:尿激酶联合芪苈强心胶囊对老年心肌梗死患者疗效显著,不良反应较少。

Objective ：To explore the clinical effect of Urokinase combining with Qili Qiangxin capsule in the treatment of 80 cases elderly patients with myocardial infarction .Methods ：80 cases elderly patients with myocardial in-farction in our hospital were selected .The patients were randomly and averagely divided into treatment group and control group ,the patients in control group were given urokinase and other conventional therapy ,the patents in treatment group were given the same treatment as control group and meanwhile given the Qili Qiangxin capsule treatment .Observed the changes of brain natriuretic peptide （BNP） levels in two groups before and after 4 weeks treatment ,and observer the ad-verse reactions occur in two groups after the followed up 5 months .Results ：After 4 weeks treatment ,the levels of BNP in two groups were obvilusly decreased compared with prior treatment （ P 〈 0 .05） ;the levels of BNP in the treatment group was lower than in control group ,showed significant difference , （ P 〈 0 .05 ） ;five months follow-up treatment found that the incidence of adverse reactions in the control group was higher than that in the treatment group （P〈 0 .05） . Conclusion ：The application of Urokinase combined Qili Qiangxin capsule has the significant effect on the treatment of myocardial infarction ,and shows fewer adverse reaction ,higher clinical value .