循证药学服务对临床合理应用抗生素的干预作用研究

Research of intervention effect by evidence-based pharmacy for clinical rational application of antibiotics

目的探索循证药学服务对临床合理应用抗生素的干预作用。方法 100例呼吸道感染患者,随机分为观察组和对照组,各50例。两组患者均遵守循证药学的治疗方式,对照组采用红霉素肠溶胶囊治疗,观察组采用青霉素钠治疗。对比疗效。结果观察组治疗3、5、7 d后的临床治疗效果(32.00%、70.00%、96.00%)优于对照组(24.00%、40.00%、64.00%)(P<0.05)。观察组临床症状改善时间均短于对照组(P<0.05)。结论呼吸道感染患者在遵守循证药学的治疗方式上使用青霉素钠治疗效果显著。

Objective To investigate intervention effect by evidence-based pharmacy for clinical rational application of antibiotics. Methods A total of 100 patients with respiratory tract infection were randomly divided into observation group and control group, with 50 cases in each group. Both groups received treatment based on evidence-based pharmacy. The control group received erythromycin enteric-coated capsules for treatment, and the observation group received penicillin sodium. Their curative effects were compared. Results The observation group had better clinical effects in 3, 5, 7 d after treatment （32.00%, 70.00%, 96.00%） than the control group （24.00%、40.00%、64.00%） （P〈0.05）. The observation group had all shorter improvement time of clinical symptoms than the control group （P〈0.05）. Conclusion Implement of penicillin sodium based on evidence-based pharmacy shows precisely curative effect for respiratory tract infection patients.