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清髓剂量预处理异基因造血干细胞移植治疗年龄≥155岁高危恶性血液系统疾病12例临床分析

Clinical studies of myeloablative dose conditioning prior to allogeneic hematopoietic stem cell transplantation for treatment of 12 patients over 55 years with high-risk malignant blood diseases
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摘要 高龄恶性血液系统疾病患者对化疗反应差、缓解率低、复发率高，且治疗过程中合并症多、治疗相关死亡率高，复杂染色体核型、继发原因等高危因素多。异基因造血干细胞移植（allo-HSCT）是有效的治疗手段，但是移植相关死亡率（TRM）高。我们采用清髓剂量预处理方案对12例年龄≥55岁高危恶性血液系统疾病患者进行allo-HSCT，现报告如下。
作者 卢岳 吴彤 刘德琰 曹星玉 熊敏 张建平 周葭蕤 陆道培
机构地区 河北燕达陆道培医院干细胞治疗科
出处 《中华血液学杂志》 CAS CSCD 北大核心 2016年第8期708-711,共4页 Chinese Journal of Hematology
关键词 异基因造血干细胞移植 恶性血液系统疾病 预处理方案 移植治疗 高危因素 临床分析 年龄 剂量
分类号 R733 [医药卫生—肿瘤] R457.7 [医药卫生—治疗学]
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参考文献15

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二级参考文献8

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中华血液学杂志
2016年 第8期

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