妊娠期高血压疾病患者NT-proBNP检测的临床意义

Clinical significance of NTpro BNP detection in patients with hypertensive disorder complicating pregnancy

目的目的探讨妊娠期高血压疾病患者NT-proBNP与病情严重程度、心功能不全相关性。方法选取80例妊娠期高血压疾病患者,主要表现为妊娠期高血压疾病、轻度子痫前期、重度子痫前期、子痫,按心功能不全分为心功能不全异常组和正常组,测定NT-proBNP浓度。结果 NT-proBN与妊娠期高血压疾病严重程度有相关性,与心功能不全呈正相关。结论妊娠期高血压疾病患者中,NT-proBNP是预测心功能不全、反映病情严重程度很好的一项实验室生化指标,同时可以指导治疗。

Objective To investigate the relationship between NT-proBNP and severity of disease and cardiac insufficiency in patients with hypertensive disorder complicating pregnancy. Methods 80 cases of hypertensive disorder complicating pregnancy were selected according to the severity of the disease in pregnancy induced hypertension, mild preeclampsia, severe preeclampsia, eclampsia, according to the heart function were divided into cardiac insufficiency group and normal group, determined NT-proBNP concentration. Results NT-proBNP was correlated with the severity of hypertensive disorder complicating pregnancy, and was positively correlated with cardiac insufficiency. Conclusion In patients with hypertensive disorder complicating pregnancy, NT-proBNP is a laboratory biochemical indicator that predicts cardiac insufficiency and is a good indicator of the severity of the disease, as well as guidance for treatment.