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HER2阳性胃癌的靶向治疗 被引量:3

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摘要 人表皮生长因子受体2(human epidermal growth factor receptor 2,HER2/neu)是一种原癌基因,具有酪氨酸激酶活性,与肿瘤的发生发展密切相关。正常情况下HER2处于非激活状态,当受到体内外某些因素作用被激活后,可从多个途径影响肿瘤细胞的生物活动,如参与调控细胞增殖与细胞凋亡,促进肿瘤细胞生长;
出处 《消化肿瘤杂志(电子版)》 2016年第1期4-9,共6页 Journal of Digestive Oncology(Electronic Version)
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