1例神经囊虫病患者的药学监护

Pharmaceutical care on a patient with neurocysticercosis

1例49岁男性患者,以头部胀痛伴双下肢无力3 d入院,诊断为脑囊虫病。入院后先后给予卡马西平片、复方苯巴比妥钠溴化钠片抗癫痫,甘露醇注射液、甘油果糖注射液脱水降颅内压,地塞米松磷酸钠注射液抗炎,奥美拉唑肠溶胶囊预防应激性溃疡,阿苯达唑片及吡喹酮片驱虫治疗。临床药师对该例患者进行全程药学监护,优化治疗方案,合理地遴选驱虫治疗药物及抗癫痫药物,并密切监测患者用药过程中可能出现的血糖、肝功、肾功能异常等不良反应,同时对患者进行用药教育。治疗30 d后,患者病情稳定出院。

One 49-year-old male patient was admitted to hospital mainly because of distending pain of head and weakness of both lower extremities for 3 days. His clinical diagnosis was cerebral cysticercosis. After hospitalization, the patient received the anti-epileptic therapy with carbamazepine tablets and phenobarbital and sodium bromide tablets, mannitol injection and glycerin and fructose injection for reducing cranial hypertension, anti-inflammatory therapy with dexamethasone sodium phosphate injection. Omeprazole enteric-coated capsules were used to prevent the occurrence of stress ulcer, albendazole tablets and praziquantel tablets were used for anti-cysticercosis treatment. Clinical pharmacists supervised the entire treatment in order to optimize the therapeutic regimen by selecting more appropriate anti-cysticercosis medications and anti-epileptic medications. Moreover, the potential adverse drug reactions like blood glucose abnormality, liver function abnormality and renal insufficiency were monitored regularly, and the patient was given medication education. The patient was in a stable condition and discharged on the 30^th day.