克罗恩病病人睡眠质量与疾病活动度及负性情绪的相关性分析

Analysis of relationship between sleep quality and disease activity and negative emotion in patients with Crohn's disease

[目的]分析克罗恩病(CD)病人睡眠质量与疾病活动度、焦虑和抑郁情绪之间的关系。[方法]采用匹兹堡睡眠质量指数量表(PSQI)、Best克罗恩病疾病活动指数(CDAI)、汉密尔顿焦虑量表(HAMA)和汉密尔顿抑郁量表(HAMD)对在炎症性肠病专科门诊就诊及肛肠科住院的108例CD病人进行测评。[结果]病人PSQI总分为(8.40±2.26)分,睡眠障碍发生率达67.6%;CDAI总分为(158.97±35.76)分,HAMA总分为(7.79±2.30)分、HAMD总分为(8.73±2.48)分;PSQI总分及其各维度与CDAI、HAMA和HAMD总分呈正相关(P<0.05)。[结论]CD病人睡眠质量欠佳,临床应重视其与疾病活动度、焦虑和抑郁情绪之间的相关关系,并采取针对性措施提高病人的睡眠质量。

Objective：To analyze the relationship between sleep quality and disease activity,anxiety and depression in patients with Crohn＇s disease（CD）.Methods：A total of 108 cases of CD patients from inflammatory bowel disease outpatient clinic and anorectal department hospitalied were investigated by using Pittsburgh sleep quality index（PSQI）,Best Crohn＇s disease activity index（CDAI）,Hamilton Anxiety Scale（HAMA）and Hamilton Depression Scale（HAMD）.Results：Patient＇s PSQI total score was 8.40±2.26.The incidence rate of sleep disorder was 67.6%.The total score of CDAI was 158.97±35.76.The total score of HAMA was 7.79±2.30.And the total score of HAMD was 8.73±2.48.The total score of PSQI and its dimensions were positively correlated with CDAI,HAMA and HAMD total score and most of dimensions（P〈0.05）.Conclusion：CD patients sleep quality is poor.Clinical should pay attention to its relationship with disease activity,anxiety and depression.One should taking pertinent measures to improve the quality of sleep of patients.