常规治疗联合心脉隆注射液治疗慢性心力衰竭的效果及意义

The Effect of Xinmailong Injuction Combined with Conventional Treatment with Chronic Heart Failure

目的探究心脉隆注射液与西医联合治疗慢性心力衰竭的效果,评价心脉隆注射液的临床药用价值。方法将2013年1月至2014年1月我院收治的283例慢性心力衰竭患者随机分为试验组（中西医联合治疗,147例）和对照组（西医常规治疗,136例）,观察并记录患者临床症状、心脏左室射血分数（Left ventricular ejection fractions,LVEF）和B型利钠肽（B-type natriuretic peptide,BNP）。结果经过3周的治疗后,试验组患者较对照组患者临床症状减轻,试验组LVEF低于对照组,差异有统计学意义（t=3.342,P=0.001）,同时,试验组BNP较对照组低,差异有统计学意义（t=3.132,P=0.002）,试验组患者的治疗效果的总有效率（92.6%）明显较对照组治疗效果的总有效率（74.8%）提高,差异有统计学意义（χ^2=125.34,P=0.045）。结论在慢性心力衰竭西医常规治疗基础上联合使用心脉隆注射液,可显著降低患者的心脏负荷,改善患者的慢性心力衰竭症状。

Objective To observe the effect of Xinmailong injection combined with conventional treatment of chronic heart failure and to evaluate the clinical application value. Methods Two hundred and eighty-three hospitalized patients with chronic heart failure from January 2013 to January 2014 were enrolled and randomly divided into treatment group（conventional treatment combined with Xinmailong Injection,n=147） and control group（conventional treatment,n=136）. The clinical feature,LEVF（Left Ventricular Ejection Fractions） and BNP（B-type natriuretic peptide） were observed. Results After treatment for three weeks,the clinical feature of treatment group was improved significantly, and the level of LVEF（t =3.342,P =0.001） were higher than the control group and BNP（t =3.132,P =0.002） were lower than the control group,and the Efficiency were higher than the control group,the differences were statistically significant（χ^2=125.34,P =0.045）. Conclusion On basis of conventional treatment in treating chronic heart failure, the adding of Xinmailong injection can lower the cardiac load of patients effectively,decrease the level of BNP, and improve the quality of life of patients with chronic heart failure.