中医院金黄色葡萄球菌临床分布及耐药性变迁

Clinical distribution and changes of drug resistance of Staphylococcus aureus in hospital of traditional Chinese medicine

目的了解中医院分离金黄色葡萄球菌的分布及其耐药性变迁，为预防和控制医院感染提供参考。方法对2012年1月～2014年12月湖北省中医院住院患者送检的各类标本进行分离培养、细菌鉴定和药敏分析。结果3年间金黄色葡萄球菌在阳性菌株中检出逐年增多；痰标本中检出最多；主要分离于脑外科和呼吸内科患者；非限制级、限制级和特殊级抗菌药物耐药率在整体上呈下降趋势。结论金黄色葡萄球菌分离率逐年上升，抗菌药物分级管理取得初步成效，应预防抗菌药物的过度使用或不合理使用。

Objective To investigate the distribution and drug resistance of Staphylococcus aureus in hospital of traditional Chinese medicine, to provide reference for the prevention and control of hospital infections. Methods From January 2012 to December 2014, various specimens from hospital inpatients of Hubei Provincial Hospital of Traditional Chinese Medicine were isolated and cultured. Then the bacterial identification and sensitivity analysis were performed. Results In 3 years, Staphylococcus aureus strains detected in positive strains were increasing year by year, which were mostly found in sputum specimens. The main source is department of cerebral surgery and respiratory medicine. Non restricted, restricted and special drug resistance rate showed an overall downward trend. Conclusion Staphylococcus aureus isolated rate is increased year by year, antimicrobial drug classification management system has achieved initial success, we should prevent overuse and unreasonable use of antibiotics.