乳腺癌术后皮瓣下积液伴感染的临床治疗分析

Clinical treatment of postoperative infection with effusion under breast flaps of breast cancer

目的分析乳腺癌患者术后出现皮瓣下积液伴感染的治疗效果,为其临床治疗提供参考依据。方法选取2012年7月-2014年7月在医院接受治疗的乳腺癌术后出现皮瓣下积液伴感染患者86例为研究对象,按随机数字表法分为两组,各43例;对照组采用中心负压引流,试验组采用硅胶负压引流球引流,比较两组患者皮瓣下积液各项指标及有效率。结果试验组平均每日引流量、伤口愈合时间及体内置管时间均明显低于对照组;两组患者总治愈率均达100.0%,但试验组治疗过程中换药次数为6次,克林霉素总用量为4.2克,庆大霉素总使用量为1 900万单位,患者治愈时间为7d;对照组治疗过程中换药次数为21次,克林霉素总用量为9.6克,庆大霉素总使用量为4 300万单位,患者治愈时间为19d。结论通过硅胶负压引流球引流方法及抗菌药物等综合治疗能改善乳腺癌术后出现皮瓣下积液伴感染患者治疗效果及提高患者术后生活质量。

OBJECTIVE To analyze the therapeutic effect of breast cancer patients with postoperative infection and effusion under skin flap,so as to provide the basis for clinical treatment.METHODS A total of 86 breast cancer patients with postoperative infection and effusion under skin flap in the hospital from Jul.2012 to Jul.2014 were selected as study objects,and randomly divided into two groups,with 43 cases in each group.Control group used central drainage,test group used silicone suction drainage ball,and fluid accumulation indicators and cure rates of the two groups of patients were compared before and after the treatment.RESULTS The average daily drainage,wound healing and body catheter time of test group were significantly lower than those of control group.The overall cure rates of the two groups of patients were up to 100%.During the treatment,test group had six times of dressing change,4.2g of clindamycin,19 million units of gentamicin,and seven days of cure time;and control group had 21 times of dressing change,9.6g of clindamycin,43 million units of gentamicin,and 19 days of cure time.CONCLUSIONThe combined treatment method of silica suction drainage ball and antibacterial drugs appears to improve breast cancer patients with postoperative infection and effusion under skin flap and improve the quality of life of patients.