不同肺叶切除术对Ⅰ～Ⅱ期非小细胞肺癌患者术后肺功能和生活质量的影响比较

Effect of Video-assisted Thoracoscopic Lobectomy and Traditional Thoracotomy Lung Resection on Lung Function and Quality of Life of Stage Ⅰ～ Ⅱ Non-small Cell Lung Cancer

目的比较电视胸腔镜肺叶切除术与传统开胸肺叶切除术对Ⅰ-Ⅱ期非小细胞肺癌术后肺功能和生活质量的影响。方法按照实际手术方式将85例Ⅰ-Ⅱ期非小细胞肺癌患者分为实验组（电视胸腔镜肺叶切除术）和对照组（传统开胸肺叶切除术），比较2组患者手术和术后随访情况。结果实验组患者术中出血量、术后胸腔引流量、术后下床时间及术后住院时间均明显低于对照组，差异具有统计学意义（P〈0．05）；2组术后6个月局部复发率和远处转移率比较，差异无统计学意义（P〉0．05）；实验组患者术后3个月VC、FEVI、MVV均明显高于对照组（P〈0．05）；实验组患者术后3个月生理状况和功能状况评分均明显高于对照组（P〈0．05）。结论电视胸腔镜手术创伤小、术中出血少、术后恢复时间短、肺功能恢复快，生活质量高，临床应用价值较高。

Objective To explore the effect of video-assisted thoracoscopic lobectomy and traditional thoracotomy lung resection on lung function and quality of life of stage I - II non-small cell lung cancer. Methods 85 cases of stage I - 1I non- small cell lung cancer were divided into the experiment group and the control group. The operation and postoperative follow up were compared. Results The intraoperative blood loss, postoperative thoracic drainage, postoperative time out of bed, postopera- tive hospitalization time of the experiment group were lower than those of the control group （P 〈 O. 05） ; There had no significant difference in the local recurrence rates and distant metastatic rate between the 2 groups （P 〉 0.05 ） ;The VC .FEVI. MVV of the experiment group were higher than those of the control group （ P 〈 0.05 ） ; The scores of physiological status, functional status of the experiment group were higher than those of the control group （ P 〈0. 05 ）. Conclusion Video-assisted thoracoscopic lobecto- my for stage I - II non-small cell lung cancer has small surgical trauma,less intraoperative bleeding, short postoperative recover- y time ,fast lung function recovery, and high quality of life, it has high value of clinical application.