射频消融辅助治疗转移性骨肿瘤的疗效研究

Curative Effect of Radiofrequency Ablation Auxiliary Treatment for Metastatic Bone Tumors

目的探讨射频消融辅助治疗转移性骨肿瘤的临床效果,以期提高临床诊治水平。方法选取52例转移性骨肿瘤患者作为研究对象,分成2组,对照组26例,予放化疗等对症处理;观察组26例,辅助射频消融,观察治疗前后生活质量、NAS评分等指标变化。结果对照组6个月生存率为23.08%、18个月以上生存率为15.38%,观察组6个月生存率为11.53%、18个月以上生存率为34.62%,两组比较差异有统计学意义(P<0.05);VAS评分上,治疗前与治疗后3 d、3个月两组内VAS评分比较差异均有统计学意义(P<0.05),治疗后3 d、3个月两组间比较差异有统计学意义(P<0.05);治疗前后两组在躯体、情绪、社会功能、疲劳、便秘方面比较差异均有统计学意义(P<0.05),治疗后躯体、情绪、社会功能、疲劳、便秘组间比较差异有统计学意义(P<0.05)。结论射频消融辅助治疗转移性骨肿瘤能提高患者生活质量,延长生存时间。

Objective To investigate the clinical efficacy of adjuvant treatment of radiofrequency ablation for metastatic bone cancer,in order to improve the clinical diagnosis and treatment. Methods 52 cases of metastatic bone cancer patients were divided into 2 groups, each with 26 cases, the control group received chemotherapy and other symptomatic treatment, the observa- tion group received assisted radiofrequeney ablation, quality of life, NAS scores and other indicators before and after treatment were observed. Results In the control group, 6-month survival rate was 23.08 percent, 18-month survival rate was 15.38%, in the observation group, 6-month survival rate was 11.53 % , 18-month survival rate was 34.62% , the difference was statistically sig- nificant（P 〈0.05）;VAS score before treatment and 3d, 3 months after treatment had statistically significant differences （P 〈 0.05 ）, VAS score 3 d and 3 months after treatment between the 2 groups had statistically significant differences （ P 〈 0.05 ） ; the 2 groups before and after treatment in physical, emotional, social functioning, fatigue, constipation, had statistically significant differ- ences （ P 〈 0.05 ） , after treatment, physical, emotional, social functioning, fatigue, constipation between the 2 groups had statistical- ly significant differences （ P 〈 0.05 ） . Conclusion Radiofrequency ablation adjuvant therapy for metastatic bone cancer can im- prove the quality of life and prolong survival time.