支原体脂质相关膜蛋白致病机制的研究进展

Pathogenic mechanisms on mycoplasma lipid-associated membrane proteins

支原体是一种没有细胞壁的原核细胞型微生物。支原体膜表面含有丰富的脂质相关膜蛋白(Lipid-associated membrane proteins,LAMPs),LAMPs在支原体对宿主的致病过程中起着重要的作用。了解支原体LAMPs致病机制可为开发针对性疫苗和有效药物提供依据。根据近年来发表的文献,对支原体LAMPs的结构特点及其致病机制的研究进展予以综述。

Mycoplasma is a kind of prokaryotic microorganism without cell wall. There are copious lipid-associated membrane proteins（ LAMPs） on the membrane surface of mycoplasma. LAMPs play an important role in the mycoplasma infection process for host cells. It is to well understand the pathogenic mechanisms of mycoplasma LAMPs that the foundation has been set up in developing specific vaccines or effective drugs. According to the published literatures in recently years,this review focused on the structural features and the progress of pathogenic mechanisms of mycoplasma LAMPs.