两级轴流血泵基于血液损伤的数值分析

Numerical Analysis of Two-stage Axial Blood Pump Based on Blood Damage

植入式微型轴流血泵工作时的高叶轮转速会增加血液损伤的风险。本文试图通过将轴流血泵设计成两级的方式来减小发生溶血和血栓的风险。本文对两级及单级轴流血泵在进口流量5L/min、出口压力100mm Hg的工况下进行数值模拟,并对比了溶血程度及血小板活化程度。研究结果显示,两级轴流血泵溶血程度优于单级设计,而血小板活化程度差于单级设计。在溶血程度和血小板活化程度的指标上,两级低-高扬程叶轮组合血泵设计优于两级等扬程和两级高-低扬程叶轮组合血泵设计。在降低植入式微型轴流血泵的血液损伤风险方面,本文的研究结果可为其提供一定的理论基础和新的设计思路。

The implantable miniaturized axial blood pump works at a high rotational speed,which increases the risk of blood damage.In this article,we aimed to reduce the possibility of hemolysis and thrombosis by designing a twostage axial blood pump.Under the operation conditions of flow rate 5L/min and outlet pressure of 100 mm Hg,we carried out the numerical simulation on the two-stage and single-stage blood pumps to compare the hemolysis and platelet activation state.The results turned out that the hemolysis index of two-stage axial blood pump was better while the platelet activation state was worse than those of single stage design.On the index of hemolysis level and platelet activation state,the design of the two-stage pump with the low and high-head impeller combination was better than the two-stage pump with the equal heads,or the high and low-head impeller combination.In terms of reducing the risk of blood damage for implantable miniaturized axial blood pump,the research result can provide some theoretical basis and new design ideas.