不同年龄段化脓性扁桃体炎患儿合并肺炎支原体感染的临床分析

Clinical analysis of suppurative tonsillitis with mycoplasma pneumoniae infection in different age children

目的探讨不同年龄段化脓性扁桃炎患儿合并肺炎支原体感染情况。方法选取2014年5月~2015年12月我院收治化脓性扁桃体炎患儿105例为研究组,根据年龄分为研究A组（6个月~3岁）和研究B组（4~13岁）;选取同期我院收治呼吸道感染患儿112例为对照组,根据患儿年龄分为对照A组（6个月~3岁）和对照B组（4~13岁）,比较各组患儿间肺炎支原体特异性抗原（MP-Ig E）和肺炎支原体特异性抗体（MP-Ig M）阳性率及白细胞介素13（IL-13）水平。结果研究A组患儿MP-Ig E阳性率低于研究B组,研究B组MP-Ig E阳性率高于对照B组,比较有统计学意义（P〈0.05）;研究A组与对照A组,对照A组与对照B组MP-Ig E阳性率比较均无统计学意义（P〉0.05）。研究A组患儿MP-Ig M阳性率低于研究B组,研究B组MP-Ig M阳性率高于对照B组,比较有统计学意义（P〈0.05）;研究A组与对照A组,对照A组与对照B组MP-Ig M阳性率比较均无统计学意义（P〉0.05）。研究A组IL-13水平低于研究B组、对照A组和对照组B组,研究B组IL-13水平低于对照A组、对照组B组,比较有统计学意义（P〈0.05）;对照组A组和对照B组两组患儿IL-13水平比较无统计学意义（P〉0.05）。结论化脓性扁桃体炎6个月~3岁患儿不易感染MP,4~13岁患儿易感染MP,临床中应根据患儿年龄有针对性诊治。

Objective To investigate suppurative tonsillitis with Mycoplasma pneumoniae infection in different age children. Methods 105 cases with suppurative tonsillitis in May 2014 to December 2015 in our hospital were selected as the study group, and all cases were divided into the study group A（6 months- 3 years old） and the study group B（4- 13 years old） according to age; 112 cases with upper respiratory tract infection were selected as control group, and all cases were divided into the control group A（6 months- 3 years old） and the control group B（4- 13 years old） according to age. MP-Ig E, MP-Ig M positive rates and IL-3 levels of four groups were compared. Results MP-Ig E positive rate of the study group A was lower than the study group B, and MP-Ig E positive rate of the study group B was higher than the control group B, which showed significant difference（P〈0.05）. MP-Ig E positive rate of the study group A showed no significant difference with the control group A, and the control group A showed no significant difference with the control group B（P〈0.05）. MP-Ig M positive rate of the study group A was lower than the study group B, MP-Ig M positive rate of the study group B was higher than the control group B, which showed significant difference（P〉0.05）. MP-Ig M positive rate of the study group A showed no significant difference with the control group A, and the control group A showed no significant difference with the control group B（P〈0.05）. IL-13 level of the study group A was lower than the study group B, the control group A and the control group B, and IL-13 level of the study group B was lower than the control group A and the control group B, which showed significant difference（P〉0.05）; IL-13 levels of the control group A and the control group B showed no significant difference（P〉0.05）. ConclusionSuppurative tonsillitis in 6 months- 3 years old children are not susceptible to MP, and 4- 13 years old children are susceptible to MP. In clinical work, treatment should be targeted for according to the age of the children.