摘要
目的分析1型糖尿病(T1DM)患儿血清维生素A和维生素D水平变化及其临床意义。方法 2012年2月至2015年1月南阳市中心医院儿科收治住院的T1DM患儿45例,为T1DM组,其中27例合并酮症酸中毒(DKA)。同期选取本院健康体检儿童38例,为对照组。采用酶联免疫吸附法测定血清维生素A和维生素D水平。结果 T1DM患儿血清维生素A和维生素D水平均低于对照组,差异有统计学意义(P<0.05)。单纯T1DM患儿血清维生素A和维生素D与T1DM合并DKA患儿比较差异均无统计学意义(P>0.05)。结论及时、足量补充维生素A和维生素D可能降低或延迟儿童T1DM发病。
Objective To analyze the level of serum vitamin A and vitamin D in children with T1 DM and its clinical significance.Methods From February 2012 to January 2015 in Pediatrics Department of Nanyang Central Hospital,45 children with T1 DM were selected as T1 DM group,27 cases with DKA;38healthy children undergoing physical examination at the same time period were selected as control group.The level of vitamin A and vitamin D were detected by ELISA.Results The level of serum vitamin A and vitamin D in T1 DM group was lower than that in control group（P〈0.05）.The level of serum vitamin A and vitamin D had no significant differences in children with simple T1 DM and children combined with DKA（P〉0.05）.Conclusion Timely and adequate supplement of vitamin A and vitamin D may reduce or delay the onset of T1 DM in children.
出处
《中国中西医结合儿科学》
2016年第4期406-408,共3页
Chinese Pediatrics of Integrated Traditional and Western Medicine
