慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者采用无创正压通气治疗的疗效观察

Clinical observation of chronic obstructive pulmonary disease combined with Type Ⅱ respiratory failure treated by noninvasive positive pressure ventilation therapy

目的:探析无创正压通气治疗方案对慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者的临床效果.方法:选取2012-07/2015-05年河南省南阳市第二人民医院收治的慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者80例作为研究对象,根据治疗方案差异分为对照组(n=40)和观察组(n=40),对照组采用常规慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭治疗方案,观察组采用联合无创呼吸机治疗.对比两组患者临床救治效果.结果:记录对比两种治疗方案下患者酸碱度(pH)、氧分压(PaO_2)、二氧化碳分压(PaCO_2)等指标变化,观察组患者改善程度均明显优于对照组,差异有统计学意义(P<0.05).结论:对慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者除了常规药物和对症治疗外,联合无创正压通气方案临床应用效果更为突出,改善患者身体机能恢复,值得重视推广.

AIM： To discuss the clinical effect of chronic obstructive pulmonary disease combined with Type Ⅱ respiratory failure treated by noninvasive positive pressure ventilation therapy.METHODS： A total of 80 cases of chronic obstructive pulmonary disease combined with Type Ⅱ respiratory failure admitted into the Second People＇s Hospital of Nanyang City were chosen as study objects and divided into control group（ n = 40） and observation group（ n = 40）. The patients in the control group were given conventional therapy for chronic pulmonary disease combined with Type Ⅱ respiratory failure,while the patients in the observation group were treated with noninvasive positive pressure ventilation therapy. The clinical effects of both groups were compared.RESULTS： According to the records of all indicators of both groups,the pH,PaO_2,PaCO_2 in the observation group were better than those in the control group,with statistically significant differences（ P0.05）. CONCLUSION： As for chronic pulmonary disease combined with Type Ⅱ respiratory failure,in spite of the conventional therapy,noninvasive positive pressure ventilation therapy has shown a better effect in helping patients recover,as a result,worth promoting.