降钙素原检测对重症急性胰腺炎患者临床价值的研究

Research of clinical value by procalcitonin detection for severe acute pancreatitis patients

目的通过血清降钙素原(PCT)检测,探讨PCT在重症急性胰腺炎(SAP)中的临床价值。方法 120例SAP患者,根据感染存在的诊断标准分为感染组(92例)和非感染组(28例),记录两组患者入院24、48 h时PCT水平。结果入院24、48 h感染组患者血清中PCT水平(4.22±0.55)、(7.24±0.88)ng/ml明显高于非感染组(1.09±0.35)、(1.68±0.51)ng/ml,差异具有统计学意义(P<0.01)。结论 SAP患者早期血清PCT的测定,不但有助于早期诊断是否合并感染,而且对评估病情和判断后续治疗具有重要指导意义。

Objective To detect serum procalcitonin（PCT） and to investigate clinical value by PCT in severe acute pancreatitis（SAP）. Methods A total of 120 SAP patients were divided by diagnosis standard of infection into infection group（92 cases） and non-infection group（28 cases）. PCT levels in 24 and 48 h after admission were recorded in both groups. Results The infection group had obviously higher serum PCT levels in 24 and 48 h after admission as（4.22±0.55） and（7.24±0.88） ng/ml than（1.09±0.35） and（1.68±0.51） ng/ml in the non-infection group. Their difference had statistical significance（P〈0.01）. Conclusion Early detection of serum PCT in SAP patients can not only provide early diagnosis of complicated infection, but also contain important guiding significance for disease evaluation and sequential treatment judgment.