艾滋病相关淋巴瘤的CT影像表现及病理结果

CT imaging appearances and pathology results of AIDS related lymphoma

目的分析艾滋病(acquired immunodeficiency syndrome,AIDS)合并淋巴瘤的CT影像表现及病理结果,探讨其影像表现及病理特点,提高对AIDS相关淋巴瘤的认识。方法回顾分析39例经临床活检病理确诊为AIDS合并淋巴瘤患者的影像资料,总结分析AIDS合并淋巴瘤的影像表现及特点。结果 39例艾滋病合并淋巴瘤的病理类型均为非霍奇金淋巴瘤(non-Hodgkin's lymphoma,NHL);影像学表现中淋巴结结内病变共39例,以淋巴结肿大为主,其中腋窝淋巴结肿大16例,颈部淋巴结肿大9例,纵隔及肺门淋巴结肿大7例,腹腔淋巴结肿大6例,腹股沟淋巴结肿大1例;淋巴结结外病变34例,以占位性病变为主,累及部位广泛,包括软组织肿块20例,发生于肝12例,骨骼/软骨10例,消化道8例,肺6例,肾上腺4例,肾及脾各3例,胰腺及肌肉各2例,腮腺、胆囊、前列腺及精囊腺、膀胱各1例。结论艾滋病相关淋巴瘤主要以NHL为主,广泛累及淋巴结及淋巴结以外器官,淋巴结外病变发生率高、且常多脏器受累是其影像学特点,艾滋病相关淋巴瘤的影像表现与病理符合度高,但确诊仍需结合其病理结果。

Objective To analyze and investigate the CT imaging features and pathological results of AIDS related lymphoma,improving the cognition of acquired immunodeficiency syndrome（ AIDS） related lymphoma. Methods Data of 39 cases with biopsypathologically proved AIDS-related lymphoma（ ARL） were retrospectively analyzed, the specific imaging features of ARL were summarized. Results All the pathological types of 39 cases with ARL were non-Hodgkin ＇s lymphomas（ NHL）; There were 39 lymphomas of lymph node,the main manifestations were enlargement of lymph nodes,including axillary lymph nodes（ n = 16）,cervical lymph nodes（ n = 9）,mediastinal and lung lymph nodes（ n = 7）,abdominal lymph nodes（ n = 6）,inguinal lymph node（ n = 1）; there were 34 extranodal lymphomas,the main manifestations were space-occupying lesions,including soft tissue mass（ n = 20）,liver（ n =12）,bone / cartilage（ n = 10）,digestive tract（ n = 8）,lung（ n = 6）,adrenal gland（ n = 4）,kidney（ n = 3）,spleen（ n = 3）,pancreas（ n=2）,muscle（ n = 2）,parotid（ n = 1）,cholecyst（ n = 1）,prostate（ n = 1）,seminal vesicle（ n = 1） and bladder（ n = 1）,respectively. Conclusion NHL is the primary type of ARL. The main imaging features were extensive lymphnodes involvement and extranodal lesions. Though the imaging manifestations of AIDS complicated with lymphoma were well correlated with pathology findings,the imaging findings still need to be combined with pathological findings to obtain definite diagnosis.