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中晚期胃癌的脉象分布规律及其与肿瘤标志物CEA、CA199的关系 被引量:4

Pulse Distribution of Advanced Gastric Cancer and Its Relationship with Tumor Markers CEA and CA199
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摘要 目的:探讨中晚期胃癌的脉象分布规律及其与肿瘤标志物CEA、CA199的关系。方法:搜集符合纳入标准的中晚期胃癌患者150例,运用计算机脉象仪采集患者脉象,分析患者脉象的分布规律,并运用logistic逐步回归分析中晚期胃癌脉象与肿瘤标志物之间的关系。结果:脉象与年龄、性别和胃癌TNM分期有一定的关系。涩脉、细数脉组CA199水平与其他组比较,差异均有统计学意义(P<0.05);涩脉、虚脉组CEA水平与其他组比较,差异均有统计学意义(P<0.05)。CEA的升高是虚脉的保护因素(OR值=-3.243<1),CA199的升高是涩脉的危险因素(OR值=14.000>1)。结论:中晚期胃癌常见的脉象为:涩脉、细数脉、虚脉、弱脉等,中晚期胃癌的脉象与肿瘤标志物CEA、CA199有一定的关系,CA199的升高对涩脉的出现有一定的影响,CEA的升高导可能使虚证减少。 Objective: To investigate the pulse distribution in advanced gastric cancer, as well as the rela- tionship with tumor markers CEA and CA199. Methods: The 150 cases of patients with advanced gastric cancer met the inclusion criteria were collected; the pulse was collected by computer pulse instrument; and pulse dis- tribution was analyzed, and relationship between pulse and tumor markers in advanced gastric cancer was ana- lyzed with logistic regression analysis. Results: Pulse with age, gender and TNM staging of gastric cancer show a certain relationship. Astringent pulse, pulse breakdown CA199 level group compared with other groups, the dif- ferences were statistically significant (P〈0.05); astringent pulse, pulse virtual group CEA levels compared with other groups, the differences were statistically significant (P〈0.05). CEA increase was protective factors imaginary veins (OR=-3.243〈1); elevated CA199 is a risk factor for Shibuya veins (OR=14.000〉1). Conclusion: The common pulse of advanced gastric cancer are astringent pulse, pulse breakdown, false pulse, weak pulse, etc.; the pulse of advanced gastric cancer with tumor markers CEA and CA199 show a certain relationship; CA199 increase emer- gence of astringent vein have a certain impact; CEA elevated lead may appear to reduce the deficiency.
出处 《中医药导报》 2016年第17期24-26,共3页 Guiding Journal of Traditional Chinese Medicine and Pharmacy
基金 国家科技部基础性工作重点项目(2013FY114400)
关键词 中晚期胃癌 脉象 涩脉 CEA CA199 分布规律 advanced gastric cancer pulse astringent pulse CEA CA199 distribution
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