针刺结合穴位注射治疗缺血性中风后抑郁症临床观察

Clinical Observation of Acupuncture plus Acupoint Injection for Depression After Ischemic Stroke

目的观察针刺结合穴位注射对缺血性中风后抑郁症瘀血阻络证患者抑郁症状以及生活质量的改善。方法将符合本研究的纳入标准和排除标准的患者随机分为治疗组和对照组。治疗组用针刺结合穴位注射治疗,对照组口服氟西汀,分别于治疗前和治疗2个月后进行汉密尔顿抑郁量表(HAMD)、日常生活能力评分量表(Barthel指数)测定。结果治疗2个月后治疗组抗抑郁疗效与对照组比较差异无统计学意义(P>0.05)。治疗2个月后治疗组日常生活能力评分量表评分优于对照组(P<0.05)。结论针刺结合穴位注射对缺血性中风后抑郁症瘀血阻络证患者的抑郁症状改善确有疗效,且治疗2个月后相比较,疗效无显著差异;对患者生活质量的提高方面,针刺结合穴位注射疗法优于药物治疗。

Objective To observe the efficacy of acupuncture plus acupoint injection in improving the depression state and quality of life（QOL） in patients with depression after ischemic stroke（syndrome differentiated as blood stagnation obstructing collaterals）.Method According to the inclusion and exclusion criteria,the eligible subjects were enrolled and randomized into a treatment group and a control group.The treatment group was intervened by acupuncture plus acupoint injection,while the control group was by oral administration of Fluoxetine.They were evaluated by using the Hamilton Depression Scale（HAMD） and Barthel Index（BI） before treatment and after 2-month treatment.Result After 2-month treatment,there was no significant difference in comparing the anti-depression efficacy between the two groups（P〈0.05）.The BI score of the treatment group was significantly better than that of the control group after 2-month treatment（P〈0.05）.Conclusion Acupuncture plus acupoint injection is effective in improving the depression state in the patients with depression after ischemic stroke（syndrome differentiated as blood stagnation obstructing collaterals）;after 2-month treatment,it can produce an equivalent therapeutic efficacy compared with oral administration of Fluoxetine.Acupuncture plus acupoint injection is superior to the control in improving the QOL of the patients.