儿童原发性夜间遗尿症的发病机制和影像学研究进展

Pathogenesis progress and imaging advance in children with primary nocturnal enuresis

原发性夜间遗尿症(Primary nocturnal enuresis,PNE)给患儿及其家庭带来严重负担,其病因和发病机理至今仍存在争议,诸多研究手段都被用于在PNE的发病机制中进行探索。近年来多模态磁共振成像研究已发现PNE患儿存在多个脑区及功能缺陷、神经环路连接和脑网络属性的异常,随着影像技术的进步,我们将能采用更多的技术手段对PNE患儿发病的神经机制进行深入探索。

Primary nocturnal enuresis （PNE） bring serious burden to the children and their families, whose etiology and pathogenesis are still controversial. Many research methods are used to investigate the pathogenesis of PNE. In recent years, multiple brain regions and functional defects in children with PNE, neural circuit connection and the abnormal of brain net- work properties have been found by muhi-modality magnetic resonance imaging. With the progress of imaging technology, we will use mo~ technique to explore the neural mechanism of PNE children.