冠心病及其合并2型糖尿病患者的冠脉CT影像特点分析

Analysis of Coronary CT Imaging Features of Patients with Coronary Heart Disease and Coronary Heart Disease Complicated with Type 2 Diabetes Mellitus

目的探讨冠心病及其合并2型糖尿病患者的冠脉CT影像特点。方法回顾性分析2012年5月-2015年5月入我院就诊的88例确诊冠心病患者临床资料,根据其合并2型糖尿病情况将其分为糖尿病组(n=32)和非糖尿病组(n=56)。两组受试者均行128排极速螺旋CT冠状动脉血管造影检查,对比其冠脉病变支数、冠脉病变分布位置及病变钙化特点差异。结果 32例糖尿病组患者左/右冠状脉主要血管节段共检出96条病变血管,56例非糖尿病组患者则共124条病变血管;两组冠脉双支病变率、弥散性病变率及冠脉病变血管分布情况比较均无统计学意义(P>0.05);糖尿病组多支病变率及钙化斑块率分别为46.9%和60.4%,均显著高于非糖尿病组的17.9%和20.2%,差异均具有统计学意义(P<0.05)。结论冠心病合并2型糖尿病患者冠脉CT影像多存在钙化斑块及多支病变特点,需引起临床重视。

Objective To investigate the coronary CT imaging features of patients with coronary heart disease and coronary artery disease complicated with type 2 diabetes mellitus. Medlods The clinical data of 88 patients diagnosed with coronary heart disease who were treated in our hospital between May 2012 and May 2015 were analyzed retrospectively. According to the status of being complicated with type 2 diabetes mellitus, the patients were divided into diabetes group （n=32） and non-diabetes group （n=56）. The two groups of subjects were examined by 128 speed spiral CT coronary angiography. The number of diseased coronary arteries, distribution of coronary artery lesions and characteristics of calcified lesions were compared. Results In 32 patients in diabetes group, 96 diseased blood vessels were detected in the main blood vessel segments of left/right coronary artery, and 124 diseased blood vessels were detected in 56 patients in the non-diabetic group. There were no significant differences in the rate of double diseased branches of coronary arteries, rate of diffuse lesions and the distribution of diseased coronary arteries between the two groups （P〉0.05）. The rates of multi-vessel lesions and calcified plaques in the diabetic group （46.9%, 60.4%） were significantly higher than those in the non-diabetic group （17.9%, 20.2%） （P〈0.05）. Conclusion Most coronary CT images of patients with coronary heart disease complicated with type 2 diabetes mellitus show calcified plaque and multi-vessel lesions, which needs clinical attention.