fMRI低频振幅比在海员心理评估方面的比较分析

The comparative analysis of fractional amplitude of low-frequency fluctuation on the meatal health status of seafarers by using FMRI

目的采用静息态功能磁共振成像技术(functional magnetic resonance imaging,f MRI)探究海员和普通被试之间的低频振幅比(fractional amplitude of lowfrequency fluctuation,f ALFF)差异。材料与方法全部被试分为心理健康海员(health seafarers,HS)、亚健康海员(sub-health seafarers,sub HS)和健康被试(health people,HP)3组,计算每个被试的低频振幅比,采用统计检验方法找出对照组间具有显著差异的体素点,对照自动解剖学模版(automated anatomical labeling,AAL),检测出f ALFF具有显著差异的脑区。结果作为一种特殊的职业,海员的脑功能活动具有可塑性。相较于HP,海员f ALFF的主要差异集中在额叶,相较于HS-HP,sub HS-HP在额叶的差异显著减弱。除额叶外,sub HS相较于HS在颞叶、楔前叶、扣带回等脑区亦呈现显著差异。结论长期从事海上作业可能导致海员脑功能活动出现变化,部分海员甚至出现心理亚健康状况,该研究为保障海员的心理健康和航海安全作业提供帮助。

Objective：To explore the differences of fractional amplitude of lowfrequency fluctuation（f ALFF） between seafarers and health people,by using the technique of resting state functional magnetic resonance imaging.Materials and Methods：All the subjects were divided into three groups,mental sub-health seafarers（sub HS）,health seafarers（HS） and health people（HP）.Then calculate the f ALFF of each subject,Finally,a statistical method was used to find the voxels which had significant difference between control group according to the Anatomical Automatic Labeling（AAL） template.Results：As a special profession,the brain activity of seafarers has plasticity.the main difference of seafarers＇ f ALFF were concentrated on parietal lobe compared with HP.the difference of f ALFF on parietal lobe between sub HS-HP were significantly decreased than that of HP-HS.Besides parietal lobe,the brain area of sub HS including temporal lobe,precuneus and cingulate cortex also appear significant differences compared with HS.Conclusion：Engaged in offshore occupation for a long time may lead to the change of brain functional activity,some seafarers even appear mental sub-health condition.The study can provide help for the protection of mental health of seafarers and the security of maritime operations.