消化内科慢性萎缩性胃炎的临床规范治疗效果分析

Analysis of Clinical Effect of Chronic Atrophic Gastritis in the Digestive Department of Internal Medicine

目的探讨消化内科慢性萎缩性胃炎临床规范治疗效果。方法病例资料来源为我院2012年12月至2014年7月64例慢性萎缩性胃炎患者,根据双盲随机方式分为对症组和干预组,其中对症组患者治疗方案为常规药物,干预组患者治疗方案为常规药物联合替普瑞酮,对比疗效、幽门螺杆菌转阴情况和6个月复发情况。结果所有数据经卡方检验显示,干预组症状改善优良率显著高于对症组,P<0.05;干预组幽门螺杆菌转阴率明显较高、6个月复发率明显较低,显著优于对症组,P<0.05。结论常规药物联合替普瑞酮治疗可作为消化内科慢性萎缩性胃炎临床规范治疗方案,疗效确切,复发低,转阴率高,值得推广。

Objective To investigate the clinical effect of chronic atrophic gastritis in the treatment of chronic atrophic gastritis. Methods Clinical data source in our hospital from December 2012 to 2014 July 64 cases of chronic atrophic gastritis patients, according to double-blind randomly divided into symptomatic group and intervention group, which group symptomatic treatment routine drug intervention group treatment for routine drug joint teprenone, curative effect contrast, helicobacter pylori negative and 6 months recurrence. Results All the data by chi square test showed that the intervention group, the symptoms improve the excellent and good rate was significantly higher than that in the symptomatic group, P〈0.05; intervention group of Helicobacter pylori negative significantly higher rate, six month relapse rate was lower and was significantly better than that in the symptomatic group （P〈0.05）. Conclusion Routine medicine combined with teprenone treatment can be as department of gastroenterology; chronic atrophy gastritis clinical standard treatment, curative effect, low recurrence rate, high conversion rate, worthy of promotion.