摘要
目的探讨不同剂量卡维地洛治疗充血性心力衰竭的药效。方法选取充血性心力衰竭患者62例为研究对象,并将其随机分为低剂量组与高剂量组,低剂量组在进行常规心力衰竭治疗的基础上给予2.5 mg、bid卡维地洛进行治疗,高剂量组在进行常规心力衰竭治疗的基础上给予卡维地洛治疗,剂量从2.5 mg、bid开始每2周增加剂量,指导10 mg、bid或者最大耐受剂量。对比两组患者的治疗情况。结果治疗后两组换心率、心功能分级以及心胸比例与治疗前有明显差异,(P<0.05)差异具有统计学意义,组间比较也有明显差异,(P<0.05)差异具有统计学意义。结论使用卡维地洛对充血性心力衰竭患者进行治疗,高剂量能够显著改善患者的心功能和LVEF。
Objective To study the effect of different doses of carvedilol in the treatment of congestive heart failure efficacy. Methods A total of congestive heart failure patients with 62 cases as the research object, and the randomly divided into low dose group and high dose group, low dose group on the basis of conventional treatment of heart failure given 2.5 mg bid carvedilol treatment, high dose group in on the basis of conventional treatment of heart failure treated with carvedilol, dose from 2.5 mg bid began to increase the dose every 2 weeks, guiding 10 mg bid or the maximum tolerated dose. Treatment of patients in the two groups were compared. Results After treatment, two groups Heart rate, cardiac functional grading and cardiothoracic ratio before and after the treatment has obvious difference,（P〈0.05） difference has statistical significance, the comparison between groups also have obvious difference,（P〈0.05）, the difference was statistically significant. Conclusion The use of carvedilol in treatment of patients with congestive heart failure and high dose could significantly improve the patient＇s cardiac function and LVEF.
出处
《中国医药指南》
2016年第23期8-9,共2页
Guide of China Medicine
